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متن کامل


اطلاعات دوره: 
  • سال: 

    2015
  • دوره: 

    2
  • شماره: 

    2
  • صفحات: 

    700-719
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    207
  • دانلود: 

    0
چکیده: 

Delivering Perishable products to customers as soon as possible and with the minimum cost has been always a challenge for producers and has been emphasized over recent years asthe global market becoming more competitive. In this studya multi-objective mix integer non-linear programming model is proposed to maximize both profits of a distributer and the total freshness of the several products to be delivered to customers with respect to their demands and with consideration of different soft time windows for each customer, heterogeneous distribution fleet and customer selection option for the distributer. The proposed model is solved with TH method. The two genetic algorithm and simulated annealing algorithm are used to solve large-sized problems. Finally, their results are compared to each other when the optimization software becomes unable of solution representation.

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بازدید 207

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اطلاعات دوره: 
  • سال: 

    2023
  • دوره: 

    9
  • شماره: 

    3
  • صفحات: 

    313-328
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    20
  • دانلود: 

    0
چکیده: 

The current article examines the trends and performance of research on the types of effects of the COVID-19 epidemic and the different management strategies of Perishable Goods supply chain disruptions during 2 years (2020-2022) using bibliometric and network analysis based on the data set from the Scopus database using VOSviewer software. The analysis designates that Kumar A. has been the most influential author in Perishable Goods supply chain research during the COVID-19 pandemic, and India has contributed the most in this field. The most repeated keywords were resilience, food supply, and Perishable food supply chain. Citation analysis indicated that resilience and sustainability are the mainstream of research in articles with high citations. The network analysis also disclosed that resilience and sustainability are the key themes in the clusters. Furthermore, strategies for managing disruption during the COVID-19 pandemic were extracted from the highly-cited articles, which are presented in this article.

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بازدید 20

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اطلاعات دوره: 
  • سال: 

    1398
  • دوره: 

    9
  • شماره: 

    2 (پیاپی 17)
  • صفحات: 

    179-193
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    909
  • دانلود: 

    451
چکیده: 

در بازارهای رقابتیِِ کالای فاسد شدنی، تعیین قیمت کالا و ایجاد فرصت برای مشتری برای تسریع در فروش کالا از طریق تخفیف، امری حیاتی به شمار می رود. عموماً با گذشت عمرِ کالاهای فاسد شدنی، ارزش آن نزد مشتری کاهش می یابد. در این شرایط برای تشویق به خرید، سیاست های مختلفی از جمله تخفیف یا کاهش قیمت فروش مؤثر است. تاکنون در ادبیات پژوهش مدلی برای تعیین زمان بهینه ی اعلام کاهش قیمت ارائه نشده است؛ در حالی که اعلام زودهنگام یا دیرهنگام قیمت سود بنگاه را کاهش می دهد؛ بنابراین در این مقاله مدلی با ویژگی های معرفی شده در سطح بنگاه تحلیل می شود. در مدل سازیِ مسئله فرض شده است با اعلام کاهش قیمت، نرخ تقاضا تغییر محسوس دارد و نرخ تقاضا تابعی از قیمت و زمان است. همچنین نرخ تقاضا در زمان تخفیف، ابتدا نسبت به زمان افزایشی در نظر گرفته شده است و سپس با گذشت زمان، این نرخ کاهش می یابد. هدف مدل تعیین مقادیر بهینه ی قیمت فروش، زمان تخفیف و اندازه ی سفارش است تا سود کل در بازه ای مشخص و تک دوره ای حداکثر شود. پس از مدل سازی مسئله، نشان داده می شود که تابع سود تابعی مقعر است و قیمت و زمان تخفیف بهینه منحصر به فرد است. سپس با استفاده از الگوریتم ابتکاری برگرفته از ادبیات پژوهش، میزان سفارش بهینه با تعیین قیمت بهینه و زمان بهینه ی تخفیف محاسبه شده است.

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
اطلاعات دوره: 
  • سال: 

    1393
  • دوره: 

    32
  • شماره: 

    272
  • صفحات: 

    34-49
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    1378
  • دانلود: 

    266
چکیده: 

در سال های اخیر، ژن درمانی از طریق siRNA (Small interfering RNA) توجهات زیادی را معطوف خود ساخته است. این پدیده بر اساس PTGS (Post transcriptional gene silencing) استوار است. به دلیل نقایص وکتورهای ویروسی، استفاده از وکتورهای Non viral برای انتقال نوکلئیک اسید مورد توجه قرار گرفته است. درست است که وکتورهای Non viral نسبت به انواع ویروسی، میزان ترانسفکشن کمی دارند، اما Safety وکتورهای غیر ویروسی بسیار بیشتر می باشد. قابلیت های کلیدی siRNA مثل انطباق پذیری بالا، کاربرد در دوزهای کم و همه کاره بودن آن، سبب استفاده از siRNA در روش های انتقال ژن شده است. با این حال، دارای نقایصی مثل تحریک سیستم ایمنی و Off target silencing نیز می باشد. در این مقاله، بیشتر سعی بر این بود تا مشکلاتی که در سر راه انتقال siRNA به سلول وجود دارد، بررسی شود. با توجه به اطلاعاتی که در دست است، گفته می شود که پیشرفت هر چه بیشتر siRNA Delivery می تواند در آینده به یک روش قابل اتکا جهت درمان بیماری هایی که پایه ژنتیکی دارند، مبدل گردد.

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نویسندگان: 

FARSI E. | YOUSEFI YEGANEH B. | MONIRI A.

اطلاعات دوره: 
  • سال: 

    2018
  • دوره: 

    31
  • شماره: 

    7 (TRANSACTIONS A: Basics)
  • صفحات: 

    1074-1081
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    268
  • دانلود: 

    0
چکیده: 

Due to the rapid development of technology in recent years, market competition and customer expectations have increased more than ever. In this situation, it is vital for businesses survival to determine the appropriate policy for inventory control, pricing, and routing, and decisions regarding each of them are often made separately. If the products have a Perishable nature, it will be more important to determ ine the above policies. For integration of the decision-making concerning the three key components of the supply chain, i. e. pricing, routing, and inventory control, two mathematical models were developed for a two-echelon supply chain of Perishable items with direct shipment, where fixed lifetime is assumed in one model and random lifetime in another, so that profit is maximized. The proposed mathematical model was solved using the CPLEX solver package of the GAMS software for specification of the optimal policy of the supply chain. The results demonstrated that the CPU time needed for solving the mathematical model for Perishable items with random lifetime was less than that for fixed lifetime, while the value of the objective function for products with fixed lifetime was greater than that for products with random lifetime.

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بازدید 268

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اطلاعات دوره: 
  • سال: 

    2019
  • دوره: 

    15
  • شماره: 

    4
  • صفحات: 

    709-721
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    161
  • دانلود: 

    0
چکیده: 

Sustainability in the supply chain means pushing the supply chain to focus on social, economic and environmental aspects, and addressing the existing problems in the traditional supply chain. Considering the importance of evaluating supply chain networks, especially in the field of Perishable commodities, this paper aimed to design a mathematical model for the reverse supply chain of Perishable Goods, taking into account the sustainable production system. In this research, four objective functions were considered to maximize profitability and the level of satisfaction with the use of technology, minimize costs and measure environmental impacts. The results of the implementation of the proposed model for a manufacturing company show that objective functions are sensitive to demand, so the change in demand changes the objective functions, in particular the profitability function.

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
اطلاعات دوره: 
  • سال: 

    1393
  • دوره: 

    -
  • شماره: 

    50
  • صفحات: 

    165-184
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    1067
  • دانلود: 

    223
چکیده: 

لطفا برای مشاهده چکیده به متن کامل (PDF) مراجعه فرمایید.

شاخص‌های تعامل:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

بازدید 1067

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اطلاعات دوره: 
  • سال: 

    2021
  • دوره: 

    34
  • شماره: 

    7
  • صفحات: 

    1766-1777
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    21
  • دانلود: 

    0
چکیده: 

This paper develops a bi-objective optimization model for the integrated production-distribution planning of Perishable Goods under uncertainty. The first objective seeks to maximize the profit in a specific supply chain with three levels: plants, distribution centers, and in the last level, customers. Since transportation is one of the major pollution sources in a distribution problem, the second objective is to minimize their emission. In the considered problem, the decisions of production, location, inventory, and transportation are made in an integrated structure. In developing the demand function, the effect of the product freshness and the price is formulated. Besides, to encourage customers, three strategies, including perished product return, discount, and credit policies, are proposed. Also, robust optimization is utilized to cope with the operational uncertainty of some cost parameters. To prove the applicability of this research and the feasibility of the environmental aspect, a case study is conducted. Finally, the numerical computations on the case study provide a trade-off between the environmental and economic goals and indicate a 37.5 percent increase in the profit using the developed model.

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اطلاعات دوره: 
  • سال: 

    2019
  • دوره: 

    12
  • شماره: 

    4
  • صفحات: 

    136-153
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    105
  • دانلود: 

    0
چکیده: 

Recently, following the raise in expense pressures led to lower economic growth, an increasing number of manufacturers have begun to investigate eventuality of handling returned product in a more cost-effective and proper procedure. Significance of Reverse Logistics (RL) is becoming greater due to various governmental, societal, and environmental reasons. Number of papers present in the literature on RLs is a well index of its importance. In some industries, appropriately collected returned products could be used as raw material for another product, increasing Supply Chain (SC) profits and reducing the waste. Since, Perishable Goods have a limited shelf-life, they can be reusable if they are collected before they reach a critical time. Accordingly, in the present study, a Mixed Integer Linear Programming (MILP) model was introduced for a network of closed-loop SC with recycling of returned Perishable Goods, involving suppliers, producers, retailers, together with collection and disposal centers, in a multi-product, multi-period, and multi-level basis. To do this, a case study was performed on milk and yogurt products of a company in dairy industry. The model was solved and analyzed using GAMS software. Results obtained from assessment of the model indicated that, timely collection of Perishable Goods and their use in production of new products reduces total costs of Perishable SC network.

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بازدید 105

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اطلاعات دوره: 
  • سال: 

    2021
  • دوره: 

    6
  • شماره: 

    26
  • صفحات: 

    0-0
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    80
  • دانلود: 

    0
چکیده: 

In this paper, a bi-objective pharmaceutical supply chain network under uncertainty demand and transportation costs is modeled and developed. To control the uncertainty parameters, the robust optimization method is considering. The main objective of this paper determines the number and location of potential facilities such as drug manufacture centers and drug distribution centers by considering the minimizing the total costs and minimizing the maximum unsatisfied demand for distribution of drugs to demand zones. In this paper, production time, Delivery, and drug Perishable time is also considered in modeling. To solve the model, an example is designed and the multi-decision TH method is used. The results obtained the model shows this method is effective in finding the Pareto front at the right time. The results obtained the model shows this method is effective in finding the Pareto front at the right time. The results obtained the model shows this method is effective in finding the Pareto front at the right time.

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بازدید 80

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